Medical Professional Home Page About Rocaltrol About Chronic Kidney Disease hypoparathyroidism Important Safety Information
 
What are some possible side effects of Rocaltrol treatment?1
•  Adverse effects of calcitriol are similar to those seen with excessive vitamin D intake (ie, hypercalcemia syndrome or calcium intoxication). However, due to the short biological half-life of calcitriol, elevated serum calcium levels normalize within a few days of treatment withdrawal (ie, much faster than treatment with vitamin D3 preparations).
•  Tell your doctor if you experience the following signs and symptoms of vitamin D toxicity: weakness, headache, sleepiness, nausea, vomiting, dry mouth, constipation, muscle or bone pain, metallic taste, lack of appetite or stomach ache, weight loss, change in urine, eye pain or sensitivity, abnormal sensations, or dizziness.
•  The most common safety issues seen in pediatric patients are mild, transient episodes of elevated serum calcium levels, elevated serum phosphate levels or the combination of both, which are managed by reducing the dose or temporarily discontinuing use.
References:
1. Rocaltrol [package insert]. Parsippany, NJ: Validus Pharmaceuticals; 2009.
 
Full Prescribing Information for Rocaltrol

Important Safety Information for Rocaltrol® (calcitriol) Capsules and Oral solution
Rocaltrol should not be taken if there are symptoms of abnormally elevated vitamin D or calcium levels or if you are allergic to any product ingredient. Taking too much vitamin D can cause high calcium levels, which could trigger serious health problems and may require immediate medical attention. Dosage adjustments of Rocaltrol may be required if other medications are initiated or discontinued; do not stop taking other medications without your physician's knowledge. Potential side effects of Rocaltrol are, in general, similar to effects of taking too much vitamin D. Report early symptoms of elevated vitamin D or calcium including weakness, headache, somnolence, nausea, vomiting, dry mouth, constipation, muscle or bone pain, metallic taste, and anorexia, abdominal pain or stomach ache, to your doctor.