Medical Professional Home Page About Rocaltrol About Chronic Kidney Disease hypoparathyroidism Important Safety Information
 
How does Rocaltrol work in people with Chronic Kidney Disease?
The beneficial effect of Rocaltrol (calcitriol) in metabolic bone disease in patients with chronic kidney disease appears to result from its positive effects on hypocalcemia and the overactive parathyroid gland. The parathyroid gland becomes too active in patients with chronic kidney disease and hypocalcemia.
References:
1. Rocaltrol [package insert]. Parsippany, NJ: Validus Pharmaceuticals; 2009.
2. Vitamin D. Medline Plus Web site. Available at: http://mplus.nlm.nih.gov/medlineplus/druginfo/natural/patient-vitamind.html.
 
Full Prescribing Information for Rocaltrol

Important Safety Information for Rocaltrol® (calcitriol) Capsules and Oral solution
Rocaltrol should not be taken if there are symptoms of abnormally elevated vitamin D or calcium levels or if you are allergic to any product ingredient. Taking too much vitamin D can cause high calcium levels, which could trigger serious health problems and may require immediate medical attention. Dosage adjustments of Rocaltrol may be required if other medications are initiated or discontinued; do not stop taking other medications without your physician's knowledge. Potential side effects of Rocaltrol are, in general, similar to effects of taking too much vitamin D. Report early symptoms of elevated vitamin D or calcium including weakness, headache, somnolence, nausea, vomiting, dry mouth, constipation, muscle or bone pain, metallic taste, and anorexia, abdominal pain or stomach ache, to your doctor.