Medical Professional Home Page About Rocaltrol About Chronic Kidney Disease hypoparathyroidism Important Safety Information
 
What is Rocaltrol?
Rocaltrol® is the brand name for a synthetic form of calcitriol, a metabolite of vitamin D which occurs naturally in the human body. calcitriol regulates the amount of calcium and phosphorus circulating in the bloodstream by enhancing their absorption from the gastrointestinal tract and promoting their release from bone. Evidence suggests that calcitriol may also act on the kidneys by preventing the excretion of calcium and phosphorus into the urine.

Calcitriol is the active form of vitamin D that regulates the amount of calcium and phosphorus in the bloodstream.

Calcitriol is used to manage low levels of calcium in the blood of patients whose kidneys or parathyroid glands (glands in the neck that release natural substances to control the amount of calcium in the blood) are not working normally. Low blood levels of calcium (hypocalcemia) may cause bone disease. Calcitriol works by helping the body to use more of the calcium found in foods or supplements.
References:
1. Rocaltrol [package insert]. Parsippany, NJ: Validus Pharmaceuticals; 2009.
2. Vitamin D. Medline Plus Website. Available at: http://mplus.nlm.nih.gov/medlineplus/druginfo/natural/patient-vitamind.html.
 
Full Prescribing Information for Rocaltrol

Important Safety Information for Rocaltrol® (calcitriol) Capsules and Oral solution
Rocaltrol should not be taken if there are symptoms of abnormally elevated vitamin D or calcium levels or if you are allergic to any product ingredient. Taking too much vitamin D can cause high calcium levels, which could trigger serious health problems and may require immediate medical attention. Dosage adjustments of Rocaltrol may be required if other medications are initiated or discontinued; do not stop taking other medications without your physician's knowledge. Potential side effects of Rocaltrol are, in general, similar to effects of taking too much vitamin D. Report early symptoms of elevated vitamin D or calcium including weakness, headache, somnolence, nausea, vomiting, dry mouth, constipation, muscle or bone pain, metallic taste, and anorexia, abdominal pain or stomach ache, to your doctor.